Author

M. H. Gade

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Organism:bacteria (other)· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Research Focus:metabolism & bioenergetics· 1 Assay:metabolomics· 1 Assay:proteomics· 1

Frequent Co-Authors

P. Laurino· 2 shared A. Delaney· 1 shared A. M. Damry· 1 shared A. Villar-Briones· 1 shared B. P. S. Chouhan· 1 shared C. J. Jackson· 1 shared D. Martinez· 1 shared J. S. Brock· 1 shared

Activity by Year

2020-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersBiochemistry

P. Laurino

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2 papers

Recent·Most cited

Substrate dynamics contribute to enzymatic specificity in human and bacterial methionine adenosyltransferases

M. H. GADE, L. L. Tan, A. M. Damry, M. Sandhu, J. S. Brock, A. Delaney, A. Villar-Briones, C. J. Jackson, P. Laurino

This study investigates how substrate conformational dynamics influence enzymatic specificity in human and bacterial methionine adenosyltransferases, revealing differences in catalytic promiscuity and identifying a new metabolite in cancer cells.

bioRxiv · Feb 18, 2021Biochemistry

Consequences of the divergence of Methionine AdenosylTransferase

B. P. S. Chouhan, M. H. Gade, D. Martinez, S. Toledo-Patino, P. Laurino

This study investigates the structural and functional consequences of sequence divergence in archaeal Methionine AdenosylTransferase (MAT) compared to bacterial and eukaryotic MATs.

bioRxiv · Aug 17, 2020 · PreprintEvolutionary Biology