EpCAM Aptamer siRNA chimeras: Therapeutic efficacy in epithelial cancer cells.
S. V. Elchuri, J. Balasubramanyam, L. Badrinarayanan, B. Dhaka, H. Gowda, A. Pandey, K. Subramanian, B. S. Lakshmi
This study demonstrates that EpCAM aptamer-siRNA chimeras effectively silence oncogenes in epithelial cancers, leading to tumor reduction and apoptosis.
bioRxiv · Jun 6, 2019 · PreprintCancer Biology