Nα-acetylation of EsxA is required for mycobacterial cytosolic translocation and virulence
J. Aguilera, C. B. Karki, L. Li, S. V. Reyes, Q. Zhang, C. Arico, H. Ouellet, J. Sun
This study shows that Nα-acetylation of Thr2 on EsxA is necessary for its dissociation from EsxB and subsequent mycobacterial virulence.
bioRxiv · Jan 8, 2020Biochemistry