The ER membrane protein complex governs lysosomal turnover of a mitochondrial tail-anchored protein, BNIP3, to restrict mitophagy
J. M. Delgado, L. W. Shepard, S. W. Lamson, S. L. Liu, C. J. Shoemaker
This study identifies the ER membrane protein complex as a key regulator of lysosomal BNIP3 turnover, independent of autophagy, and highlights its role in modulating mitophagy and TA protein quality control.
bioRxiv · Mar 22, 2023 · PreprintCell Biology