Author

J. M. Delgado

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1 Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:host-pathogen & immune response· 2 Research Focus:cell signaling & trafficking· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Approach:mechanistic / dynamical model· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

A. N. Kettenbach· 1 shared A. Tkatchenko· 1 shared C. J. Shoemaker· 1 shared D. M. Rogers· 1 shared F. Magnotti· 1 shared H. S. Malek· 1 shared J. B. Bliska· 1 shared L. W. Shepard· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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1 shared paperImmunology

A. N. Kettenbach

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Author profile →

3 papers

Recent·Most cited

The ER membrane protein complex governs lysosomal turnover of a mitochondrial tail-anchored protein, BNIP3, to restrict mitophagy

J. M. Delgado, L. W. Shepard, S. W. Lamson, S. L. Liu, C. J. Shoemaker

This study identifies the ER membrane protein complex as a key regulator of lysosomal BNIP3 turnover, independent of autophagy, and highlights its role in modulating mitophagy and TA protein quality control.

bioRxiv · Mar 22, 2023 · PreprintCell Biology

Phosphoprotein Phosphatase Activity Positively Regulates Oligomeric Pyrin to Trigger Inflammasome Assembly in Phagocytes

H. S. Malek, F. Magnotti, N. A. Loeven, J. M. Delgado, A. N. Kettenbach, T. Henry, J. B. Bliska

This study identifies phosphoprotein phosphatase activity as a positive regulator of oligomeric pyrin, essential for inflammasome assembly in phagocytes.

bioRxiv · Mar 23, 2022Immunology

Molecular basis for SARS-CoV-2 spike affinity for human ACE2 receptor

J. M. Delgado, N. Duro, D. M. Rogers, A. Tkatchenko, S. A. Pandit, S. Varma

This study identifies the molecular basis for SARS-CoV-2's higher affinity for human ACE2 compared to SARS-CoV using molecular dynamics simulations and free energy calculations.

bioRxiv · Sep 10, 2020 · PreprintBiophysics