Author

S. Wueest

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Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:metabolism & bioenergetics· 1 Assay:metabolomics· 1 Organism:mouse· 1

Frequent Co-Authors

C. Deisl· 1 shared D. G. Fuster· 1 shared D. Konrad· 1 shared G. Albano· 1 shared P. Kucharczyk· 1 shared

Activity by Year

2022-2022 · peak 1/yr

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5 top collaborators · 10 mutual co-author links

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1 shared paperPhysiology

C. Deisl

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1 paper

Recent·Most cited

Thiazides induce glucose intolerance through inhibition of mitochondrial carbonic anhydrase 5b in β-cells

P. Kucharczyk, G. Albano, C. Deisl, S. Wueest, D. Konrad, D. G. Fuster

This study identifies mitochondrial carbonic anhydrase 5b (CA5b) as the molecular target of thiazides, showing its inhibition leads to reduced insulin secretion and glucose intolerance in β-cells.

bioRxiv · Mar 23, 2022 · PreprintPhysiology