Author

D. Konrad

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Research Focus:metabolism & bioenergetics· 1 Assay:metabolomics· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

B. Cravatt· 1 shared B. Melillo· 1 shared C. Deisl· 1 shared D. G. Fuster· 1 shared D. Ogasawara· 1 shared E. Njomen· 1 shared G. Albano· 1 shared H. Li· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperBiochemistry

B. Cravatt

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Author profile →

2 papers

Recent·Most cited

Chemical tools to expand the ligandable proteome: diversity-oriented synthesis-based photoreactive stereoprobes

D. Ogasawara, D. Konrad, Z. Y. Tan, K. Carey, J. Luo, S. J. Won, H. Li, T. Carter, K. DeMeester, E. Njomen, S. Schreiber, R. Xavier, B. Melillo, B. Cravatt

The paper introduces photo-stereoprobes for expanding the ligandable proteome and demonstrates their use in discovering bioactive small molecules.

bioRxiv · Feb 27, 2024Biochemistry

Thiazides induce glucose intolerance through inhibition of mitochondrial carbonic anhydrase 5b in β-cells

P. Kucharczyk, G. Albano, C. Deisl, S. Wueest, D. Konrad, D. G. Fuster

This study identifies mitochondrial carbonic anhydrase 5b (CA5b) as the molecular target of thiazides, showing its inhibition leads to reduced insulin secretion and glucose intolerance in β-cells.

bioRxiv · Mar 23, 2022 · PreprintPhysiology