Harnessing the Intrinsic Photochemistry of Isoxazoles for the Development of Chemoproteomic Crosslinking Methods
M. G. Lougee, V. V. Pagar, H. J. Kim, S. X. Pancoe, R. H. Mach, B. Garcia, E. J. Petersson
This paper introduces a new photo-crosslinking method using isoxazole's intrinsic photochemistry, validated across multiple proteins in vitro and ex vivo.
bioRxiv · Dec 23, 2021Biochemistry