Skin Delivery of Modified Vaccinia Ankara Viral Vectors Generates Superior T Cell Immunity Against a Respiratory Viral Challenge
Y. Pan, L. Liu, T. Tian, J. Zhao, C. O. Park, S. Y. Lofftus, C. A. Stingley, S. Mei, X. Liu, T. S. Kupper
This study shows that skin scarification delivery of MVA vectors generates robust T cell immunity against respiratory viral challenges, outperforming other routes and suggesting its potential for vaccines like COVID-19.
bioRxiv · May 6, 2020Immunology