Resin-acid derivatives bind to multiple sites on the voltage-sensor domain of the Saker channel
M. Silvera Ejneby, A. Gromova, N. E. Ottosson, S. Borg, A. Estrada-Mondragon, S. Yazdi, P. Apostolakis, F. Elinder, L. Delemotte
This study identifies three resin-acid binding sites on the Shaker KV channel using molecular dynamics and electrophysiology, showing their role in channel activation.
bioRxiv · Jun 11, 2020Biophysics