(E)-2-Benzylidene-3-(cyclohexylamino)-2,3-dihydro-1H-inden-1-one (BCI) Induces Apoptosis Via The Intrinsic Pathway In H1299 Lung Cancer Cells
J.-W. Shin, S.-B. Kwon, Y. Bak, S. Lee, D.-Y. Yoon
This study shows that BCI induces apoptosis in NCI-H1299 lung cancer cells via the intrinsic pathway by increasing Bax, caspase-9/3, and cytochrome c release while decreasing Bcl-2.
bioRxiv · Apr 26, 2017Pharmacology & Toxicology