Degrading intestinal DAF-2 nearly doubles Caenorhabditis elegans lifespan without affecting development or reproduction
Y.-P. Zhang, W.-H. Zhang, P. Zhang, Q. Li, Y. Sun, J.-W. Wang, S.-B. O. Zhang, T. Cai, C. Zhan, M.-Q. Dong
This study shows that reducing DAF-2 in the intestine of C. elegans nearly doubles lifespan without affecting development or reproduction.
bioRxiv · Jul 31, 2021 · PreprintCell Biology