Discovery of μ,δ-Opioid receptor dual biased agonists that overcome the limitation of prior biased agonists
J. H. Lee, S.-Y. Shon, W. Jeon, S.-J. Hong, J. Ban, D. S. LEE
The paper identifies three dual biased agonists for mu and delta opioid receptors that show improved efficacy compared to existing biased agonists like Oliceridine.
bioRxiv · Jan 21, 2021Pharmacology & Toxicology