YAP/TAZ and EZH2 synergize to impair tumor suppressor activity of TGFBR2 in non-small cell lung cancer
Federica Lo Sardo, Claudio Pulito, Andrea Sacconi, Etleva Korita, Marius Sudol, Sabrina Strano, Giovanni Blandino
This study identifies YAP/TAZ and EZH2 as synergistic regulators that repress TGFBR2, a tumor suppressor, in NSCLC through both miRNA-mediated and epigenetic mechanisms.
bioRxiv · Jul 10, 2020Cancer Biology