Cancer BiologybioRxiv
YAP/TAZ and EZH2 synergize to impair tumor suppressor activity of TGFBR2 in non-small cell lung cancer
Federica Lo Sardo, Claudio Pulito, Andrea Sacconi…·Giovanni Blandino
This study identifies YAP/TAZ and EZH2 as synergistic regulators that repress TGFBR2, a tumor suppressor, in NSCLC through both miRNA-mediated and epigenetic mechanisms.
DOI 10.1016/j.canlet.2020.11.037