Supracellular contractility in Xenopus laevis embryonic epithelia regulated by extracellular nucleotides and the purinergic G-protein coupled receptor P2Y2.
Sagar D. Joshi, Timothy R. Jackson, Lin Zhang, Carsten Stuckenholz, Lance A. Davidson
The paper identifies extracellular nucleotides ATP and UTP as drivers of epithelial contractility in Xenopus embryos, mediated by the P2Y2 receptor.
bioRxiv · Jan 21, 2025 · PreprintCell Biology