Author

Sai Gayathri R

Regional Centre for Biotechnology

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Cell Biology· 1

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Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Arun Kumar Mishra· 1 shared Mahua MaulikiD· 1 shared Moulinath AcharyaiD· 1 shared Shamita SangaiD· 1 shared Sukanya Mitra· 1 shared Trisha GhoshiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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6 top collaborators · 15 mutual co-author links

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1 shared paperCell Biology

Arun Kumar Mishra

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1 paper

Recent·Most cited

Cell BiologyCell Death DiscoveryPeer-reviewedJun 5, 2026

Novel truncating Desmin mutation Arg150Stop disrupts structural integrity and cellular homeostasis by formation of persistent aggregate-like structure

Sukanya Mitra, Trisha Ghosh, Arun Kumar Mishra…·Moulinath Acharya

This study investigates a novel truncating Desmin mutation, Arg150Stop, showing it causes persistent aggregate-like structures that disrupt cellular homeostasis and cytoskeletal integrity through a toxic gain-of-function mechanism.

DOI 10.1038/s41420-026-03184-x

humanproteomics

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