Author

Saibal Chatterjee

Indian Institute of Science Bangalore

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Molecular Biology· 5

Signature Assays, Organisms & Methods

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Organism:C. elegans· 4 Approach:experimental assay· 4 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1

Frequent Co-Authors

Aniruddha Samajdar· 3 shared Tamoghna ChowdhuryiD· 3 shared Adil Rashid WaniiD· 2 shared Moumita Sardar· 2 shared Mohini SinghiD· 1 shared Pradipta Kundu· 1 shared Rohit NalavadeiD· 1 shared

Activity by Year

2020-2022 · peak 3/yr

Co-Author Collaboration Network

7 top collaborators · 9 mutual co-author links

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3 shared papersMolecular Biology

Aniruddha Samajdar

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Author profile →

5 papers

Recent·Most cited

Dauer quiescence as well as continuity of the life cycle after dauer-exit in Caenorhabditis elegans are dependent on the endoribonuclease activity of XRN-2

Tamoghna Chowdhury, Aniruddha Samajdar, Moumita Sardar, Saibal Chatterjee

The paper investigates the role of XRN-2 endoribonuclease activity in dauer state maintenance and post-dauer life cycle continuity in C. elegans, finding that its disruption leads to metabolic and developmental defects.

bioRxiv · May 2, 2022 · PreprintMolecular Biology

Biogenesis of mature piRNAs in Caenorhabditis elegans is dependent on orchestration between multiple ribonucleases and PRG-1

Aniruddha Samajdar, Tamoghna Chowdhury, Saibal Chatterjee

The paper identifies XRN-2 as an endoribonuclease involved in 5-end processing of precursor piRNAs in C. elegans, revealing its role in piRNA maturation and function.

bioRxiv · Dec 29, 2021 · PreprintMolecular Biology

XRN2-mediated regulation of tumor suppressor microRNAs is of critical pathophysiological significance in Humans

Rohit Nalavade, Tamoghna Chowdhury, Saibal Chatterjee

The paper shows XRN2 degrades specific tumor suppressor miRNAs, affecting cancer cell behavior and patient survival.

bioRxiv · Aug 20, 2021 · PreprintMolecular Biology

Endoribonuclease activity of XRN-2 is critical for RNA metabolism and survival of Caenorhabditis elegans

Moumita Sardar, Aniruddha Samajdar, Adil Rashid Wani, Saibal Chatterjee

This study characterizes the endoribonuclease activity of XRN-2 in C. elegans, showing its critical role in miRNA turnover and survival of dauer worms, and its importance in rRNA maturation for translation.

bioRxiv · Feb 25, 2021 · PreprintMolecular Biology

A multifaceted microRNA turnover complex from Caenorhabditis elegans

Mohini Singh, Adil Rashid Wani, Pradipta Kundu, Saibal Chatterjee

The paper identifies a microRNA turnover complex in C. elegans and shows it can switch between ATP-dependent and ATP-independent modes of operation.

bioRxiv · Dec 28, 2020 · PreprintMolecular Biology