Integrative genomic strategies applied to a lymphoblast cell line model reveal specific transcriptomic signatures associated with clozapine response
SAJ de With, Anil P. S. Ori, Tina Wang, Sara L. Pulit, Eric Strengman, Joana F. Viana, Jonathan S. Mill, Simone de Jong, Roel A. Ophoff
The paper investigates clozapine's molecular effects using lymphoblastoid cell lines, identifying transcriptomic and epigenomic changes linked to cholesterol and metabolic pathways.
bioRxiv · Sep 22, 2020 · PreprintGenomics