Author

Eric Strengman

Princess Máxima CenterORCID 0000-0001-9796-0507Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:database / resource· 1 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Alex JanseiD· 1 shared Anil P. S. OriiD· 1 shared Bastiaan B.J. TopsiD· 1 shared Casey CaiiD· 1 shared Douwe F. M. van der LeestiD· 1 shared Eugène T.P. VerwieliD· 1 shared Frank C. P. HolstegeiD· 1 shared Hindrik H. D. KerstensiD· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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1 shared paperGenomics

Alex JanseORCID

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2 papers

Recent·Most cited

Systematic discovery of gene fusions in pediatric cancer by integrating RNA-seq and WGS

Ianthe A. E. M. van Belzen, Casey Cai, Marc C van Tuil, Shashi Badloe, Eric Strengman, Alex Janse, Eugène T.P. Verwiel, Douwe F. M. van der Leest, Lennart A. Kester, Jan J. Molenaar, Jules P.P. Meijerink, Jarno Drost, Weng Chuan Peng, Hindrik H. D. Kerstens, Bastiaan B.J. Tops, , Jayne Y. Hehir‐Kwa

This paper develops a method to detect tumor-specific gene fusions in pediatric cancer by integrating RNA-seq and WGS, identifying 165 high-confidence fusions and their structural variants.

BMC Cancer · Jul 3, 2023Peer-reviewedGenomics

Integrative genomic strategies applied to a lymphoblast cell line model reveal specific transcriptomic signatures associated with clozapine response

SAJ de With, Anil P. S. Ori, Tina Wang, Sara L. Pulit, Eric Strengman, Joana F. Viana, Jonathan S. Mill, Simone de Jong, Roel A. Ophoff

The paper investigates clozapine's molecular effects using lymphoblastoid cell lines, identifying transcriptomic and epigenomic changes linked to cholesterol and metabolic pathways.

bioRxiv · Sep 22, 2020 · PreprintGenomics