Spatial transcriptomic profiling uncovers the molecular effects of the neurotoxicant polychlorinated biphenyls (PCBs) in the brains of adult mice
Budhaditya Basu, Nicole M. Breese, Sal Lombardi, Hui M. Wang, X. Li, Destiny Tiburcio, Zachary Niemasz, Stacy E. Beyer, Laura E. Dean, Rachel F. Marek, Michal J. Toborek, Hans‐Joachim Lehmler, Snehajyoti Chatterjee
This study investigates the molecular effects of PCB exposure on brain function in mice using spatial transcriptomics and identifies disruptions in tight junction proteins and gene expression networks.
Molecular Psychiatry · Jan 31, 2026Peer-reviewedNeuroscience