Author

Xueshu Li

University of IowaORCID 0000-0002-0881-5381Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

X. Li653 papers · Insigneo

Biology Disciplines

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Genetic & Genomic Medicine· 1 Neuroscience· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 3 Approach:statistical model· 3 Research Focus:gene regulatory network inference· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1

Frequent Co-Authors

Hans‐Joachim LehmleriD· 3 shared Pamela J. LeiniD· 2 shared Budhaditya BasuiD· 1 shared Charles E. MordauntiD· 1 shared Destiny TiburcioiD· 1 shared Hui M. WangiD· 1 shared Janine M. LaSalleiD· 1 shared Joe Jongpyo LimiD· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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3 shared papersNeuroscience

Hans‐Joachim LehmlerORCID

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3 papers

Recent·Most cited

NeuroscienceMolecular PsychiatryPeer-reviewedJan 31, 2026

Spatial transcriptomic profiling uncovers the molecular effects of the neurotoxicant polychlorinated biphenyls (PCBs) in the brains of adult mice

Budhaditya Basu, Nicole M. Breese, Sal Lombardi…·Snehajyoti Chatterjee

This study investigates the molecular effects of PCB exposure on brain function in mice using spatial transcriptomics and identifies disruptions in tight junction proteins and gene expression networks.

3 citationstop 2%

mousespatial transcriptomics

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Systems BiologybioRxivPreprintJun 4, 2025

Single-cell transcriptomics showed that maternal PCB exposure dysregulated ER stress-mediated cell type-specific responses in the liver of female offspring

Joe Jongpyo Lim, Youjun P. Suh, Xueshu Li…·Julia Yue Cui

This study uses single-cell RNA sequencing to show that maternal PCB exposure alters cell type-specific gene expression and pathways in the liver of female offspring, affecting metabolic and immune functions.

DOI 10.1101/2025.06.04.657944

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Genetic & Genomic MedicineEnvironmental ResearchPeer-reviewedJan 3, 2023

Networks of placental DNA methylation correlate with maternal serum PCB concentrations and child neurodevelopment

Julia S. Mouat, Xueshu Li, Kari E. Neier…·Janine M. LaSalle

The paper identifies placental DNA methylation modules associated with maternal PCB levels and child neurodevelopmental outcomes in the MARBLES cohort.

25 citations

humanDNA methylation

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