Hans‐Joachim Lehmler

This study shows that transferring PCB-exposed gut microbiota to offspring reproduces neurobehavioral deficits and induces sex-biased molecular changes in the brain.

This study investigates the molecular effects of PCB exposure on brain function in mice using spatial transcriptomics and identifies disruptions in tight junction proteins and gene expression networks.

This study shows that gradual heat exposure in mice triggers sex-specific changes in immune responses and metabolism, affecting cytokines, microbiota, and metabolites.

This study uses single-cell RNA sequencing to show that maternal PCB exposure alters cell type-specific gene expression and pathways in the liver of female offspring, affecting metabolic and immune functions.

The paper identifies placental DNA methylation modules associated with maternal PCB levels and child neurodevelopmental outcomes in the MARBLES cohort.