Melanocortin 4 Receptor-Dependent Mechanism of ACTH in Preventing Anxiety-Like Behaviors and Normalizing Astrocyte Proteins After Early Life Seizures
Mohamed R. Khalife, Colin Villarin, Juan Manuel Ruiz, Sam A. McClelland, Khalil Abed Rabbo, J. Matthew Mahoney, Rod C. Scott, Amanda E. Hernan
This study shows ACTH prevents anxiety-like behaviors and normalizes astrocyte proteins after early life seizures via MC4R activation in neurons and astrocytes.
eNeuro · Feb 27, 2025Peer-reviewedNeuroscience