Inflammatory cytokine profile and plasticity of brain and spinal microglia in response to ATP and glutamate
Sam Joshva Baskar Jesudasan, Somnath J. Gupta, Matthew A. Churchward, Kathryn G. Todd, Ian Robert Winship
The paper compares the response of spinal cord and brain microglia to ATP and glutamate under physiologically relevant conditions and shows that these DAMPs do not significantly modulate cytokine release, but environmental factors can alter microglial inflammatory responses.
Frontiers in Cellular Neuroscience · Apr 6, 2021Peer-reviewedNeuroscience