Kathryn G. Todd

This study shows that pleiotrophin (PTN) promotes neurite outgrowth in neurons exposed to inhibitory CSPG matrix via ALK receptor activation.

The paper compares the response of spinal cord and brain microglia to ATP and glutamate under physiologically relevant conditions and shows that these DAMPs do not significantly modulate cytokine release, but environmental factors can alter microglial inflammatory responses.

This study shows that GM1 ganglioside administration reduces microglial inflammation and modulates microglial functions, suggesting therapeutic potential for neurodegenerative diseases.