Intracellular and Dual-Site Inhibition of a bitter taste GPCR
Nitsan Dallal, Gil Daniel Paz, Noga Nir-Marom, Yael Keselman, Shir Eyal, Evgenii Ziaikin, Alon Rainish, Sam R.J. Hoare, Lior Peri, Einav Malach, Masha Y. Niv
The paper investigates the inhibitory mechanisms of TAS2R14 antagonists by analyzing mutations and computational models, revealing distinct binding sites and potencies.
Cellular and Molecular Life Sciences · Mar 30, 2026Peer-reviewedBiochemistry