Author

Shir Eyal

Hebrew University of JerusalemORCID 0009-0005-0050-9098Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Alon RainishiD· 2 shared Einav MalachiD· 2 shared Evgenii ZiaikiniD· 2 shared Masha Y. NiviD· 2 shared Nitsan DallaliD· 2 shared Gil Daniel Paz· 1 shared Lior PeriiD· 1 shared Noga Nir-Marom· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersPharmacology & Toxicology

Alon RainishORCID

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2 papers

Recent·Most cited

Pharmacology & ToxicologybioRxivPreprintJun 22, 2026

Pharmaceutical TAS2R14 Agonists Display Diverse Potency, Efficacy, and Binding-Site Sensitivity

Shir Eyal, Nitsan Dallal, Alon Rainish…·Masha Y. Niv

The paper examines how three pharmaceutical drugs activate TAS2R14 through different binding modes and efficacy, using cell-based assays and receptor mutations.

DOI 10.64898/2026.06.17.732860

humanproteomics

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BiochemistryCellular and Molecular Life SciencesPeer-reviewedMar 30, 2026

Intracellular and Dual-Site Inhibition of a bitter taste GPCR

Nitsan Dallal, Gil Daniel Paz, Noga Nir-Marom…·Masha Y. Niv

The paper investigates the inhibitory mechanisms of TAS2R14 antagonists by analyzing mutations and computational models, revealing distinct binding sites and potencies.

3 citationstop 1%

experimental assay

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