Neuregulin1 nuclear signaling influences adult neurogenesis and regulates a schizophrenia susceptibility gene network within the mouse dentate gyrus.
Prithviraj Rajebhosale, Alice Jone, Kory R. Johnson, Rohan Hofland, Camille Palarpalar, Samara Khan, Lorna W. Role, David A. Talmage
This study shows that a schizophrenia-associated Nrg1 mutation disrupts nuclear signaling in mouse dentate gyrus, altering gene expression and neurodevelopmental processes.
Journal of Neuroscience · Aug 30, 2024Peer-reviewedNeuroscience