Lorna W. Role

The paper identifies a role for Neuregulin1 nuclear back signaling in regulating dentate gyrus granule cell subtype diversity, showing that its disruption leads to increased semilunar granule cell-like cells.

This study shows that a schizophrenia-associated Nrg1 mutation disrupts nuclear signaling in mouse dentate gyrus, altering gene expression and neurodevelopmental processes.

The paper identifies two distinct subpopulations of VP cholinergic neurons that encode valence of olfactory stimuli and differentially regulate approach and avoidance behaviors.

The paper identifies basal forebrain cholinergic neurons as essential partners in threat memory engrams, showing distinct activation patterns for learned and innate threats.

The paper shows that acetylcholine in the basolateral amygdala increases during reward-related events and enhances learning of cue-reward associations in mice.

This paper develops GACh sensors, genetically-encoded fluorescent indicators for acetylcholine, validated across multiple cell types and species, revealing new insights into cholinergic transmission.