Kory R. Johnson

The paper identifies extracellular vesicles (sEVs) from EBV-transformed B-cells as a vehicle for exporting host DNA and EBV EBER1 RNA, linking peripheral EBV infection to distal tissue signaling in MS.

This study shows that triglyceride metabolism is essential for microglial activation and disease states in APOE4 microglia, with implications for modulating immune responses.

The paper identifies a role for Neuregulin1 nuclear back signaling in regulating dentate gyrus granule cell subtype diversity, showing that its disruption leads to increased semilunar granule cell-like cells.

This study investigates transcriptional and physiological changes in thalamocortical connections after unilateral whisker denervation, finding increased synaptic activity and gene expression related to glutamate receptors.

This study shows that a schizophrenia-associated Nrg1 mutation disrupts nuclear signaling in mouse dentate gyrus, altering gene expression and neurodevelopmental processes.

This study identifies a unique metabolic state in RSeT human embryonic stem cells characterized by quadrivalency, linking it to growth independence from oxygen and resistance to naive reprogramming.

This study uses proteomic techniques to show that PGRN deficiency impairs lysosomal function and proteostasis in neurons by altering pH, enzyme levels, and protein turnover.

This study identifies dysregulation of the TGFβ pathway in a mouse model of collagen VI-related disorders, linking ECM collagen VI deficiency to altered TGFβ bioavailability and muscle dysfunction.

The paper uses deep RNA sequencing to compare gene expression in the subgenual anterior cingulate cortex across major psychiatric disorders and controls, finding disorder-specific expression changes and genetic associations.

This paper performs a multivariate meta-analysis of human pluripotent stem cell datasets to assess the existence of a naive pluripotent state, finding inconsistencies and no clear transcriptomic markers for a bona fide human naive state.

The paper performs a multivariate meta-analysis of human pluripotent stem cell datasets to assess interlaboratory variability in defining naive-like pluripotent states.