Author

Samhita Gudapati

University of Pittsburgh

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Physiology· 1

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Assay:bulk RNA-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Organism:mouse· 1

Frequent Co-Authors

Arijit RoyiD· 1 shared James S.K. ShamiD· 1 shared Mi-Kyung ShiniD· 1 shared Omkar Padel· 1 shared Vsevolod Y. PolotskyiD· 1 shared Wan-Yee Tang· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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1 shared paperPhysiology

Arijit RoyORCID

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1 paper

Recent·Most cited

PhysiologybioRxivPreprintMar 7, 2026

Epigenetic Silencing of Carotid Body TRPM7 Attenuates Hypertension in Obese Mice

Mi-Kyung Shin, Arijit Roy, Omkar Padel…·Vsevolod Y. Polotsky

This study shows that reversing DNA methylation at the Trpm7 promoter in carotid bodies of obese mice reduces hypertension by decreasing Trpm7 expression and nerve activity.

DOI 10.64898/2026.03.05.709322

mouseDNA methylation

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