LiaS-dependent activation of the MadR regulon enables cross-talk between Enterococcus faecalis cell envelope defense systems
Kara S. Hood, Samie A Rizvi, Guillermo Hoppe-Elsholz, Ana Paula Streling, Diana Panesso, Shivendra Pratap, Yousif Shamoo, César A. Arias, William R. Miller
This study shows that the MadR regulon can be activated independently of MadS through cross-talk with LiaS, enhancing Enterococcus faecalis resistance to daptomycin.
bioRxiv · Jun 19, 2025 · PreprintMicrobiology