Author

Samir Kumar Brahmachari

Institute of Genomics and Integrative Biology

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Bioinformatics· 4 Genomics· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:statistical model· 5 Research Focus:gene regulatory network inference· 4 Research Focus:differential expression· 3 Organism:human· 3 Approach:benchmark study· 2 Research Focus:drug response / drug discovery· 2 Assay:bulk RNA-seq· 1 Research Focus:database / resource· 1

Frequent Co-Authors

Ashwin JainarayananiD· 3 shared Ankit Kumar PathakiD· 2 shared Prashant Sinha· 2 shared Sanjeev JainiD· 2 shared Akshara PandeiD· 1 shared Anirudh S. Chellappa· 1 shared Beena PillaiiD· 1 shared Bharat Ravi IyengariD· 1 shared

Activity by Year

2018-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersBioinformatics

Ashwin JainarayananORCID

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Drug Contraindications in Comorbid Diseases: a Protein Interactome Perspective

Kalyani Bindu Karunakaran, Madhavi K. Ganapathiraju, Sanjeev Jain, Samir Kumar Brahmachari, N. Balakrishnan

The paper identifies drug contraindications in comorbid diseases by analyzing drug target networks and their association with disease-specific protein interaction networks and pathways.

Network Modeling Analysis in Health Informatics and Bioinformatics · Mar 19, 2024Peer-reviewedBioinformatics

Invariant Genes in Human Genomes

Ankit Kumar Pathak, Ashwin Jainarayanan, Samir Kumar Brahmachari

The paper identifies 423 population-invariant genes across 60,706 human genomes, finding many are X-linked, non-expressed, and associated with disease.

bioRxiv · Aug 20, 2019 · PreprintGenomics

Intronic miRNA Mediated Gene Expression Regulation Controls Protein Crowding Inside the Cell

Prashant Sinha, Pragya Jaiswal, Ashwin Jainarayanan, Samir Kumar Brahmachari

The paper analyzes how intronic miRNAs regulate gene expression in specific cellular contexts and shows their role in controlling protein crowding through translation regulation.

Gene · Sep 4, 2018Peer-reviewedBioinformatics

Multi-scale analysis of schizophrenia risk loci: Integrating centenarian genomes and spatio-temporal expression profiles suggest the need for adjunctive therapeutic interventions for neuropsychiatric disorders.

Anirudh S. Chellappa, Ankit Kumar Pathak, Prashant Sinha, Ashwin Jainarayanan, Sanjeev Jain, Samir Kumar Brahmachari

The paper integrates centenarian genomes and spatio-temporal expression profiles to identify potential drug targets for schizophrenia, suggesting repurposed therapies for neuropsychiatric disorders.

bioRxiv · Aug 1, 2018 · PreprintBioinformatics

Intronic non-coding RNAs within ribosomal protein coding genes can regulate biogenesis of yeast ribosome

Akshara Pande, Rani Sharma, Bharat Ravi Iyengar, Vinod Scaria, Beena Pillai, Samir Kumar Brahmachari

The paper identifies and validates intronic small RNAs (isRNAs) in yeast ribosomal protein genes that may regulate ribosome biogenesis through a feed-forward loop.

bioRxiv · Mar 27, 2018 · PreprintBioinformatics