Author

Anirudh S. Chellappa

National Institute of Mental Health and Neurosciences

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 2 Bioinformatics· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Approach:benchmark study· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Sanjeev JainiD· 3 shared Biju ViswanathiD· 2 shared Meera PurushottamiD· 2 shared Ravi Kumar NadellaiD· 2 shared Anand G. SubramaniamiD· 1 shared Ankit Kumar PathakiD· 1 shared Ashwin JainarayananiD· 1 shared Bhupesh MehtaiD· 1 shared

Activity by Year

2018-2019 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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3 shared papersNeuroscience

Sanjeev JainORCID

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3 papers

Recent·Most cited

Identification and functional characterization of two novel mutations in KCNJ10 and PI4KB in SeSAME syndrome without electrolyte imbalance

Ravi Kumar Nadella, Anirudh S. Chellappa, Anand G. Subramaniam, Ravi Prabhakar More, Srividya Shetty, Suriya Prakash, Nikhil Ratna, V.P. Vandana, Meera Purushottam, Jitender S. Saini, Biju Viswanath, Parayil Sankaran Bindu, Madhu Nagappa, Bhupesh Mehta, Sanjeev Jain, Ramakrishnan Kannan

The paper identifies two novel mutations in KCNJ10 and PI4KB in SeSAME syndrome patients and shows their functional impact on Kir4.1 channel activity.

Human Genomics · Oct 22, 2019Peer-reviewedNeuroscience

Studying cellular functions in bipolar disorder: Are there specific predictors of lithium response?

Pradip Paul, Shruti Iyer, Ravi Kumar Nadella, Rashmitha Nayak, Anirudh S. Chellappa, Sheetal Ambardar, Reeteka Sud, Salil Kalarikkal Sukumaran, Meera Purushottam, Sanjeev Jain, Biju Viswanath

This study investigates cellular phenotypes in bipolar disorder patients with and without lithium response using NPCs and LCLs, finding differences in mitochondrial potential, cell viability, and gene expression related to lithium response.

bioRxiv · Sep 2, 2019 · PreprintNeuroscience

Multi-scale analysis of schizophrenia risk loci: Integrating centenarian genomes and spatio-temporal expression profiles suggest the need for adjunctive therapeutic interventions for neuropsychiatric disorders.

Anirudh S. Chellappa, Ankit Kumar Pathak, Prashant Sinha, Ashwin Jainarayanan, Sanjeev Jain, Samir Kumar Brahmachari

The paper integrates centenarian genomes and spatio-temporal expression profiles to identify potential drug targets for schizophrenia, suggesting repurposed therapies for neuropsychiatric disorders.

bioRxiv · Aug 1, 2018 · PreprintBioinformatics