Author

Samuel I Isaacson

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Citlali Solis Salas· 1 shared Jesse Goyette· 1 shared Jun Allard· 1 shared Marcus Bridge· 1 shared Nicola Coker Gordon· 1 shared Omer Dushek· 1 shared

Activity by Year

2017-2017 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 15 mutual co-author links

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1 shared paperBiophysics

Citlali Solis Salas

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1 paper

Recent·Most cited

Biophysical assay for tethered signaling reactions reveals tether-controlled activity for the phosphatase SHP-1

Jesse Goyette, Citlali Solis Salas, Nicola Coker Gordon, Marcus Bridge, Samuel I Isaacson, Jun Allard, Omer Dushek

The paper develops a biophysical assay to study tethered signaling reactions, revealing that SHP-1 activity is significantly increased by tether binding through allosteric activation and enhanced substrate concentration.

Science Advances · Mar 3, 2017Peer-reviewedBiophysics