Author

Samuel L. Cottam

Brigham Young University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Biochemistry· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cell type annotation· 1 Assay:cryo-EM· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Aaron M. Wilson· 1 shared Barry M. WillardsoniD· 1 shared Caelen A. Jones· 1 shared Cecilia S. Sanders· 1 shared Deirdre Mack· 1 shared Jesus N. Ramirez Torres· 1 shared Liam J. Moss· 1 shared Mikaila Sass· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperBiochemistry

Aaron M. Wilson

Mutual co-authors in cluster

Author profile →

1 paper

Recent·Most cited

Disease-causing mutations in the G protein β5 β-propeller disrupt its chaperonin-mediated folding trajectory

Mikaila Sass, Deirdre Mack, Riley A. Nickles, Caelen A. Jones, Jesus N. Ramirez Torres, Aaron M. Wilson, Rex L. Brunsdale, Cecilia S. Sanders, Samuel L. Cottam, Liam J. Moss, Stefano Maggi, Peter S Shen, Barry M. Willardson

This study uses cryo-EM and biochemistry to show how disease-causing mutations in Gβ5 disrupt its folding by CCT, leading to trapped intermediates and neurological disease.

bioRxiv · May 28, 2025 · PreprintBiochemistry