Benzoxaboroles are structurally unique binders of eukaryotic translation initiation factor 4E
Joshua B. Combs, D. Matthew Peacock, Gregory B. Craven, Sungwon Jung, Y Chen, Sang M. Le, Jack Taunton, Kevan M. Shokat
The paper identifies benzoxaboroles as selective binders of eIF4E, revealing stereoselective interactions and structural insights into their binding mechanism.
Journal of the American Chemical Society · Jul 9, 2026Peer-reviewedCancer Biology