Sangbhin Lee

Optogenetic activation of liver-innervating vagal sensory neurons increases anxiety-like behavior in mice.

This study shows that optogenetic activation of liver-innervating vagal sensory neurons increases anxiety-like behavior in mice by activating the NTS-LC circuit.

Magel2 in hypothalamic POMC neurons influences the impact of stress on anxiety-like behavior and spatial learning associated with a food reward in male mice

This study investigates how Magel2 gene deletion in hypothalamic POMC neurons affects stress-induced anxiety and spatial learning in male mice, revealing sex-specific behavioral impacts.

Liver-innervating vagal sensory neurons play an indispensable role in the development of hepatic steatosis and anxiety-like behavior in mice fed a high-fat diet.

This study shows that liver-innervating vagal sensory neurons contribute to hepatic steatosis and anxiety-like behavior in mice on a high-fat diet, and their removal prevents obesity and improves metabolic outcomes.