NeurosciencebioRxivPreprint
DJ-1 deficiency and aging: dual drivers of retinal mitochondrial dysfunction.
Mala Upadhyay, Johnathon Sturgis, Sanghamitra Bhattacharyya…·Vera L. Bonilha
This study investigates how DJ-1 deficiency and aging jointly impact mitochondrial function in the retina and RPE, showing reduced OXPHOS complex levels and increased mtDNA damage.
DOI 10.1101/2025.05.19.654941