Author

Vera L. Bonilha

Cleveland ClinicORCID 0000-0002-6166-5124Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Organism:mouse· 2 Assay:proteomics· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Approach:statistical model· 1

Frequent Co-Authors

Johnathon SturgisiD· 2 shared Stephanie A. HagstromiD· 2 shared Ke JiangiD· 1 shared Ke JiangiD· 1 shared Mala UpadhyayiD· 1 shared Maya Moorthy· 1 shared Sanghamitra Bhattacharyya· 1 shared

Activity by Year

2025-2025 · peak 2/yr

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7 top collaborators · 15 mutual co-author links

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2 shared papersCell Biology

Johnathon SturgisORCID

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2 papers

Recent·Most cited

Metabolic dysfunction promoted by mitochondrial DNA mutation burden drives retinal degeneration

Johnathon Sturgis, Ke Jiang, Stephanie A. Hagstrom, Maya Moorthy, Vera L. Bonilha

This study shows that mtDNA mutations in mice lead to metabolic dysfunction in the retina and RPE, impairing retinal function through altered energy metabolism and glucose transport.

bioRxiv · Jul 30, 2025 · PreprintCell Biology

DJ-1 deficiency and aging: dual drivers of retinal mitochondrial dysfunction.

Mala Upadhyay, Johnathon Sturgis, Sanghamitra Bhattacharyya, Ke Jiang, Stephanie A. Hagstrom, Vera L. Bonilha

This study investigates how DJ-1 deficiency and aging jointly impact mitochondrial function in the retina and RPE, showing reduced OXPHOS complex levels and increased mtDNA damage.

bioRxiv · May 19, 2025 · PreprintNeuroscience