Notch coordinates self-organization of germ layers and axial polarity in cnidarian gastruloids
Sanjay Narayanaswamy, Franziska Haas, Emmanuel Haillot, Elly Margaret Tanaka, Ulrich Technau
The paper shows Notch signaling coordinates germ layer formation and axial polarity in sea anemone gastruloids through a feedback loop with Wnt signaling.
bioRxiv · Sep 9, 2025 · PreprintDevelopmental Biology