Author
University of Toronto
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
3 papers
Recent·Most cited
Maximilian Billmann, Michael Costanzo, Xiang Zhang…·Charles M. Boone
The paper constructs a genome-scale genetic interaction network from 4 million double mutants in HAP1 cells, revealing conserved genetic network principles across species and uncovering novel gene functions and cancer dependencies.
Barbara Mair, Peter M. Aldridge, Randy Singh Atwal…·Shana O. Kelley
The paper presents a high-throughput CRISPR-Cas9 screening method for identifying CD47 modulators, identifying QPCTL as a key enzyme involved in its pyroglutamyl modification.
Traver Hart, Amy H.Y. Tong, Katie Chan…·Jason Moffat
The paper evaluates CRISPR/Cas9 knockout screens in human cell lines and designs an optimized gRNA library to improve gene knockout efficiency and accuracy.