Author

Sara Debic

Johns Hopkins University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Developmental Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1 Approach:statistical model· 1

Frequent Co-Authors

Jiabiao HuiD· 2 shared Xiaobin ZhengiD· 2 shared Yixian ZhengiD· 2 shared Lidya KristianiiD· 1 shared Reni Marsela· 1 shared Youngjo Kim· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

6 top collaborators · 15 mutual co-author links

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2 shared papersDevelopmental Biology

Jiabiao HuORCID

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2 papers

Recent·Most cited

Lamins promote trophoblast lineage-associated transcription and trophoblast giant cell development in placental organogenesis

Sara Debic, Jiabiao Hu, Xiaobin Zheng, Yixian Zheng

This study shows lamins are essential for placental development by supporting trophoblast giant cell polyploidization and lineage-specific gene expression.

bioRxiv · Aug 24, 2026 · PreprintDevelopmental Biology

Lamins and lineage-relevant transcription factors coordinate gene expression in lineage development

Sara Debic, Xiaobin Zheng, Jiabiao Hu, Lidya Kristiani, Reni Marsela, Youngjo Kim, Yixian Zheng

The paper shows that lamins A and B1 maintain LADs and gene expression in yolk sac endoderm by interacting with transcription factors.

bioRxiv · May 5, 2026 · PreprintDevelopmental Biology