Author

Jiabiao Hu

Carnegie Institution for ScienceORCID 0000-0002-8802-0924Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 2 Genomics· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 3 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1

Frequent Co-Authors

Xiaobin ZhengiD· 3 shared Yixian ZhengiD· 3 shared Lidya KristianiiD· 2 shared Sara Debic· 2 shared James TayloriD· 1 shared Michael E.G. SauriaiD· 1 shared Miri KimiD· 1 shared Reni Marsela· 1 shared

Activity by Year

2018-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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3 shared papersDevelopmental Biology

Xiaobin ZhengORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Developmental BiologybioRxivPreprintAug 24, 2026

Lamins promote trophoblast lineage-associated transcription and trophoblast giant cell development in placental organogenesis

Sara Debic, Jiabiao Hu, Xiaobin Zheng, Yixian Zheng

This study shows lamins are essential for placental development by supporting trophoblast giant cell polyploidization and lineage-specific gene expression.

DOI 10.64898/2026.08.21.746365

mouseexperimental assay

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Developmental BiologybioRxivPreprintMay 5, 2026

Lamins and lineage-relevant transcription factors coordinate gene expression in lineage development

Sara Debic, Xiaobin Zheng, Jiabiao Hu…·Yixian Zheng

The paper shows that lamins A and B1 maintain LADs and gene expression in yolk sac endoderm by interacting with transcription factors.

DOI 10.64898/2026.04.30.722071

mouseDNA methylation

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GenomicsMolecular CellPeer-reviewedJun 28, 2018

Lamins organize the global three-dimensional genome from the nuclear periphery

Xiaobin Zheng, Jiabiao Hu, Sibiao Yue…·Yixian Zheng

This study shows that lamins maintain TAD-TAD interactions and regulate chromatin domain interactions, which are correlated with transcription changes in mouse ES cells.

245 citationstop 1%

mouseHi-C

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