Long-read sequencing identifies aberrant fragmentation patterns linked to elevated cell-free DNA levels in cancer
Benjamin P. Berman, Sarah A. Erdman, Christina E. Wheeler, Justin Cayford, Jean‐Valéry Turatsinze, Maria Ouzounova, Marie Piecyk, Mariëlle Herzog, Lea Francoise Payen, Thomas Walter, Theresa Kathleen Kelly
The paper uses long-read sequencing to analyze cfDNA fragmentation patterns in cancer patients, identifying hypofragmentation and hyperfragmentation linked to elevated cfDNA levels.
Genome biology · Apr 10, 2026Peer-reviewedCancer Biology