Author

Lea Francoise Payen

Lyon 1 UniversitéORCID 0000-0002-1599-5886Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Cancer Biology· 1 Genetic & Genomic Medicine· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:human· 2 Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Assay:long-read sequencing· 1 Approach:statistical model· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Marie PiecykiD· 2 shared Aitor Rodríguez‐CasanovaiD· 1 shared Alexandre HarléiD· 1 shared Alexis RapiniD· 1 shared Anes Hadjadj AouliD· 1 shared Ángel Díaz‐LagaresiD· 1 shared Anne‐Marie C. DingemansiD· 1 shared Benjamin P. BermaniD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersCancer Biology

Marie PiecykORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Long-read sequencing identifies aberrant fragmentation patterns linked to elevated cell-free DNA levels in cancer

Benjamin P. Berman, Sarah A. Erdman, Christina E. Wheeler, Justin Cayford, Jean‐Valéry Turatsinze, Maria Ouzounova, Marie Piecyk, Mariëlle Herzog, Lea Francoise Payen, Thomas Walter, Theresa Kathleen Kelly

The paper uses long-read sequencing to analyze cfDNA fragmentation patterns in cancer patients, identifying hypofragmentation and hyperfragmentation linked to elevated cfDNA levels.

Genome biology · Apr 10, 2026Peer-reviewedCancer Biology

Analytical Validation of a Pan-Cancer NGS Assay for In-House Liquid Biopsy Testing: An International Multicenter Study

Gaëlle Lescuyer, Alexandre Harlé, Hari Shankar Kumar, Pantelis Constantoulakis, Nicole Pfarr, Ellen Heitzer, Clémence Michon, Gianluca Russo, Ernst‐Jan M. Speel, Marie Piecyk, Marie Husson, Georgia Christopoulou, Eva-Maria Mayr, Mai-Lan Koppermann, Christophe Passot, , Lea Francoise Payen

This study validates a pan-cancer NGS assay for liquid biopsy testing across multiple centers, showing high sensitivity and specificity for detecting genomic alterations in cfDNA.

Journal of Molecular Diagnostics · Sep 25, 2025Peer-reviewedGenetic & Genomic Medicine