Convergent evolution during host range expansion and virulence increase in a Salmonella bacteriophage
Amandine Maurin, Marie Vasse, Cécile Breyton, Carlos Zarate-Chaves, Sarah Bouzidi, Juliette Hayer, Jacques Dainat, Margaux Mesleard-Roux, François-Xavier Weill, Ignacio G. Bravo, Alexandre Feugier, Rémy Froissart
This study evolves a virulent phage to expand its host range and increase virulence, finding convergent mutations in key genes.
bioRxiv · Mar 13, 2024 · PreprintMicrobiology