Optimization of the VSV G backbone for amino terminal fusion with nanobodies allowing its retargeting to receptors of therapeutic interest.
Isoline Duquénois, Stéphanie Thébault, Sarah Johari, Hélène Raux, Malika Ouldali, Sandrine Moutel, Cécile Lagaudrière‐Gesbert, Franck Perez, Aurélie Albertini, Yves Gaudin
The paper identifies mutations in the VSV G glycoprotein that improve its functionality when fused with nanobodies, enabling specific retargeting to therapeutic receptors.
Molecular Therapy Oncology · Sep 25, 2025Peer-reviewedBioengineering