Yves Gaudin

Spatial Uncoupling of Protein Synthesis from Viral Factories during Rabies Virus Infection

This study shows that during rabies virus infection, protein synthesis occurs outside viral factories (Negri bodies) and newly synthesized viral proteins are later targeted to these compartments.

NAP1 switches from an activator to a limiter of interferon induction by trapping TBK1 in condensates

This study shows NAP1 switches from enhancing to limiting TBK1 activity through condensate formation, affecting IFN induction and linking to interferonopathies.

Optimization of the VSV G backbone for amino terminal fusion with nanobodies allowing its retargeting to receptors of therapeutic interest.

The paper identifies mutations in the VSV G glycoprotein that improve its functionality when fused with nanobodies, enabling specific retargeting to therapeutic receptors.

Structures of vesicular stomatitis virus glycoprotein G alone and in complex with a neutralizing antibody

This study reports cryo-EM structures of vesicular stomatitis virus glycoprotein G alone and in complex with a neutralizing antibody, revealing conformational changes and epitope details.